SMARCA2 ligand-6

Catalog No.: A81366
Ligands for Target Protein for PROTAC
SMARCA2 ligand-6 is a selective ligand for the SMARCA2 protein, functioning within the context of proteolysis-targeting chimera (PROTAC) technology. This compound facilitates the targeted degradation of SMARCA2, enabling researchers to study its biological functions and roles in various cellular processes. It is a valuable tool for investigating therapeutic strategies in cancer and other diseases linked to dysregulation of chromatin remodeling factors.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSMARCA2 ligand-6 is a selective ligand for the SMARCA2 protein, functioning within the context of proteolysis-targeting chimera (PROTAC) technology. This compound facilitates the targeted degradation of SMARCA2, enabling researchers to study its biological functions and roles in various cellular processes. It is a valuable tool for investigating therapeutic strategies in cancer and other diseases linked to dysregulation of chromatin remodeling factors.
Product Information
Catalog NumA81366
FormulaC18H20N6O
Molecular Weight336.39
CAS Number2408394-89-6
SMILESNC1=C(C=C(C2=C(C=CC=C2)O)N=N1)C(C=N3)=CN3C4CCNCC4
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