SR1555 is a specific inverse agonist of the retinoic acid receptor-related orphan nuclear receptor γ (RORγ), exhibiting an IC50 value of 1 μM. This compound is known to effectively inhibit TH17 cell development and function while promoting an increase in T regulatory cell frequency and downregulating IL-17 expression. SR1555 is valuable for investigating mechanisms in autoimmune disease research.
SR1555 is a specific inverse agonist of the retinoic acid receptor-related orphan nuclear receptor γ (RORγ), exhibiting an IC50 value of 1 μM. This compound is known to effectively inhibit TH17 cell development and function while promoting an increase in T regulatory cell frequency and downregulating IL-17 expression. SR1555 is valuable for investigating mechanisms in autoimmune disease research.
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