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Suc-YVAD-AMC

Fluorogenic Substrate

Suc-YVAD-AMC is a fluorogenic substrate designed for the quantification of cysteine protease activity within the proteasome. Upon cleavage by these enzymes, the compound releases the fluorescent product AMC, enabling sensitive measurement of enzymatic activity. This reagent is widely utilized in research applications focused on proteasomal function and the mechanisms of protein degradation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Substrate
CAS Number	201860-29-9
Applications	Fluorogenic Substrate
Formula	C₃₅H₄₁N₅O₁₂
Molecular Weight	723.73
SMILES	CC=1C=2C(=CC(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)NC(CCC(O)=O)=O)=O)C(C)C)=O)C)=O)CC(O)=O)=O)=CC2)OC(=O)C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.