Sulfo DBCO-PEG4-amine

Catalog No.: A81886
PROTAC Linker
Sulfo DBCO-PEG4-amine is a polyethylene glycol (PEG)-based linker designed for use in proteolysis-targeting chimera (PROTAC) synthesis. This compound facilitates targeted degradation of proteins by connecting E3 ubiquitin ligases to specific proteins of interest. Its application in PROTAC development enhances selectivity and efficacy in degradation pathways, supporting research in targeted protein modulation and therapeutic interventions.
Grouped product items
Size Price Stock Qty
5mg
$180.00
In stock
10mg
$295.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSulfo DBCO-PEG4-amine is a polyethylene glycol (PEG)-based linker designed for use in proteolysis-targeting chimera (PROTAC) synthesis. This compound facilitates targeted degradation of proteins by connecting E3 ubiquitin ligases to specific proteins of interest. Its application in PROTAC development enhances selectivity and efficacy in degradation pathways, supporting research in targeted protein modulation and therapeutic interventions.
Product Information
Catalog NumA81886
FormulaC32H42N4O10S
Molecular Weight674.76
CAS Number2055198-05-3
SMILESO=C(CCOCCOCCOCCOCCN)NCC(S(=O)(O)=O)C(NCCC(N1C2=C(C#CC3=C(C1)C=CC=C3)C=CC=C2)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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