Sulfo-NHS-LC-Biotin

Catalog No.: A45253
Fluorescent Dye
Sulfo-NHS-LC-Biotin is an amine-reactive ester derivative of biotin that serves as a fluorescent dye, facilitating bioconjugation with amine-containing biomolecules. Due to its inability to cross the intact blood-retinal barrier, it is particularly useful for studying vascular permeability in the brain and retinal vasculature. This reagent is ideal for applications in imaging and tracking biotinylated molecules in various biological contexts.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSulfo-NHS-LC-Biotin is an amine-reactive ester derivative of biotin that serves as a fluorescent dye, facilitating bioconjugation with amine-containing biomolecules. Due to its inability to cross the intact blood-retinal barrier, it is particularly useful for studying vascular permeability in the brain and retinal vasculature. This reagent is ideal for applications in imaging and tracking biotinylated molecules in various biological contexts.
Product Information
Catalog NumA45253
FormulaC20H30N4O9S2
Molecular Weight534.60
CAS Number190598-57-3
SMILESO=C(C(CC1=O)S(=O)(O)=O)N1OC(CCCCCNC(CCCC[C@H]2[C@]3([H])[C@](NC(N3)=O)([H])CS2)=O)=O
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