Super-TDU

Catalog No.: A44034
YAP Antagonist
Super-TDU is a selective YAP antagonist that disrupts the YAP-TEAD interaction. This compound has demonstrated the ability to inhibit tumor growth in gastric cancer mouse models, making it a valuable tool for research in cancer biology and therapeutic development targeting the hippo signaling pathway. Its application in studying YAP-related signaling pathways offers insights into potential treatments for various malignancies.
Grouped product items
Size Price Stock Qty
1mg
$95.00
In stock
5mg
$305.00
In stock
10mg
$505.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSuper-TDU is a selective YAP antagonist that disrupts the YAP-TEAD interaction. This compound has demonstrated the ability to inhibit tumor growth in gastric cancer mouse models, making it a valuable tool for research in cancer biology and therapeutic development targeting the hippo signaling pathway. Its application in studying YAP-related signaling pathways offers insights into potential treatments for various malignancies.
Product Information
Catalog NumA44034
FormulaC237H369N65O70S
Molecular Weight5280.92
CAS Number1599441-71-0
SequenceSer-Val-Asp-Asp-His-Phe-Ala-Lys-Ser-Leu-Gly-Asp-Thr-Trp-Leu-Gln-Ile-Gly-Gly-Ser-Gly-Asn-Pro-Lys-Thr-Ala-Asn-Val-Pro-Gln-Thr-Val-Pro-Met-Arg-Leu-Arg-Lys-Leu-Pro-Asp-Ser-Phe-Phe-Lys-Pro-Pro-Glu
Sequence shorteningSVDDHFAKSLGDTWLQIGGSGNPKTANVPQTVPMRLRKLPDSFFKPPE
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