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T-1228

LpxC Inhibitor

T-1228 is a selective inhibitor of LpxC, a critical enzyme involved in the biosynthesis of lipopolysaccharides (LPS) in Gram-negative bacteria. By inhibiting LpxC, T-1228 disrupts the formation of the bacterial outer membrane, resulting in increased membrane permeability and subsequent bacterial cell death. This compound is valuable for research focused on understanding and combating Gram-negative bacterial infections.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1884551-35-2
Applications	LpxC Inhibitor
Formula	C₂₃H₂₇N₃O₇
Molecular Weight	457.48
SMILES	O=C(N(C)[C@](C(NC)=O)(C)C(NO)=O)C(C=C1)=CC=C1C#CC2=CC=C([C@H](O)CO)C=C2.O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.