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Biological Activity
Taltirelin (TA0910) is a superagonist at thyrotropin-releasing hormone receptor (TRH-R) with an IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.67 mL | 123.33 mL | 246.66 mL |
| 0.5 mM | 4.93 mL | 24.67 mL | 49.33 mL |
| 1 mM | 2.47 mL | 12.33 mL | 24.67 mL |
| 5 mM | 0.49 mL | 2.47 mL | 4.93 mL |
*The above data is based on the productmolecular weight 405.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18250 |
|---|---|
| Actions | Agonist |
| CAS No. | 103300-74-9 |
| Formula | C17H23N7O5 |
| M. Wt | 405.41 |
| Purity | >98% |
| Synonyms | Taltirelin; TA 0910; TA-0910; TA0910; CCRIS 8513; |
| SMILES | O=C(N)[C@H]1N(C([C@H](CC2=CNC=N2)NC([C@H](CC(N3C)=O)NC3=O)=O)=O)CCC1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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