TCO-PEG4-NHS ester is a PEG-based linker utilized in the synthesis of PROTACs. Its primary mechanism involves click chemistry, specifically the inverse electron demand Diels-Alder (iEDDA) reaction with tetrazine-containing molecules. TCO-PEG4-NHS ester facilitates targeted protein degradation, making it a valuable tool for research applications in pharmacology and molecular biology, particularly in the development of novel therapeutics.
TCO-PEG4-NHS ester is a PEG-based linker utilized in the synthesis of PROTACs. Its primary mechanism involves click chemistry, specifically the inverse electron demand Diels-Alder (iEDDA) reaction with tetrazine-containing molecules. TCO-PEG4-NHS ester facilitates targeted protein degradation, making it a valuable tool for research applications in pharmacology and molecular biology, particularly in the development of novel therapeutics.
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