Fig. 1 · Structure
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TCO-PEG6-amine
PROTAC Linkers
TCO-PEG6-amine is a PEG-derived linker designed for use in the synthesis of PROTAC (Proteolysis Targeting Chimera) compounds. This linker facilitates the development of bifunctional molecules to selectively degrade target proteins via the ubiquitin-proteasome system. Its unique structure enables effective conjugation with other moieties, contributing to research applications in targeted protein degradation and molecular biochemistry.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2353409-94-4 |
| Applications | PROTAC Linkers |
| Formula | C23H44N2O8 |
| Molecular Weight | 476.60 |
| SMILES | O=C(OC1CC/C=C\CCC1)NCCOCCOCCOCCOCCOCCOCCN |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.