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TCO-PEG8-TCO

PROTAC Linkers

TCO-PEG8-TCO is a PEG-based PROTAC linker designed for the synthesis of protein-targeting chimeras. This linker facilitates the conjugation of E3 ligase recruiters and protein-targeting moieties, enhancing the stability and efficacy of PROTAC compounds. It is instrumental in advancing research in targeted protein degradation and drug discovery applications.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2353409-67-1
Applications	PROTAC Linkers
Formula	C₃₆H₆₄N₂O₁₂
Molecular Weight	716.90
SMILES	O=C(OC1CC/C=C\CCC1)NCCOCCOCCOCCOCCOCCOCCOCCOCCNC(OC2CC/C=C\CCC2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.