Tefinostat

Catalog No.: A20258
pan HDAC inhibitor
Tefinostat (CHR-2845) is a monocyte/macrophage-targeted pan HDAC inhibitor, cleaved into active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1). Anti-monocytoid lineage leukaemias activity.
Grouped product items
Product Name Price Stock Qty
Tefinostat 5mg
$315.00
In stock
Tefinostat 10mg
$543.00
In stock
Tefinostat 50mg
$1,610.00
In stock
Tefinostat 100mg
$3,220.00
In stock
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Biological Activity
Discription Tefinostat (CHR-2845) is a monocyte/macrophage-targeted pan HDAC inhibitor, cleaved into active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1). Anti-monocytoid lineage leukaemias activity.
Targets
Target Value
Product Information
Catalog Num A20258
Formula C28H37N3O5
Molecular Weight 495.61
CAS Number 914382-60-8
SMILES O=C(OC1CCCC1)[C@H](C2=CC=CC=C2)NCC3=CC=C(NC(CCCCCCC(NO)=O)=O)C=C3
Synonyms CHR-2845, CHR2845, CHR 2845
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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