Terpendole E

Catalog No.: A54763
Eg5 Inhibitor
Terpendole E is a specific inhibitor of the mitotic kinesin Eg5, targeting its motor and microtubule-stimulated ATPase activities in human cells. This compound effectively induces the formation of a monoastral spindle during the M phase of the cell cycle, making it a valuable tool for investigating mitotic processes. Terpendole E is suitable for research applications focused on cancer biology and drug discovery targeting cell division.
Grouped product items
Size Price Stock Qty
25mg
$3,925.00
In stock
50mg
$5,070.00
In stock
100mg
$7,040.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTerpendole E is a specific inhibitor of the mitotic kinesin Eg5, targeting its motor and microtubule-stimulated ATPase activities in human cells. This compound effectively induces the formation of a monoastral spindle during the M phase of the cell cycle, making it a valuable tool for investigating mitotic processes. Terpendole E is suitable for research applications focused on cancer biology and drug discovery targeting cell division.
Product Information
Catalog NumA54763
FormulaC28H39NO3
Molecular Weight437.61
CAS Number167427-23-8
SMILESC[C@]12C3=C(C4=CC=CC=C4N3)C[C@]1([H])CC[C@]5([H])[C@@]2(CC[C@@]6([H])[C@]5([C@@H](C[C@H](O6)C(C)(O)C)O)C)C
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