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tert-Butyl N-cis-(3-formylcyclobutyl)carbamate

Catalog No.: A84018
PROTAC Linker
tert-Butyl N-cis-(3-formylcyclobutyl)carbamate serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is integral in connecting E3 ligases to target proteins, thus enabling targeted degradation through the ubiquitin-proteasome system. Its unique structural properties enhance the efficiency and specificity of PROTAC synthesis, making it a valuable tool for researchers investigating protein regulation and therapeutic interventions.
tert-Butyl N-cis-(3-formylcyclobutyl)carbamate 171549-91-0 PROTAC Linker
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptiontert-Butyl N-cis-(3-formylcyclobutyl)carbamate serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is integral in connecting E3 ligases to target proteins, thus enabling targeted degradation through the ubiquitin-proteasome system. Its unique structural properties enhance the efficiency and specificity of PROTAC synthesis, making it a valuable tool for researchers investigating protein regulation and therapeutic interventions.
Product Information
Catalog NumA84018
FormulaC10H17NO3
Molecular Weight199.25
CAS Number171549-91-0
SMILESN(C(OC(C)(C)C)=O)[C@@H]1C[C@H](C=O)C1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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PROTAC > PROTAC Linker