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TGR5 agonist 3

Catalog No.: A60415
TGR5 Agonist
TGR5 Agonist 3 is a cholic acid derivative that selectively activates the TGR5 receptor, exhibiting an EC50 of 5 μM. This compound is utilized in research to explore the role of TGR5 in various metabolic processes, including glucose and lipid metabolism. Its specific action makes it a valuable tool for studying the therapeutic potential of TGR5 modulation in diseases such as obesity and diabetes.
TGR5 agonist 3 2148317-51-3 TGR5 Agonist
Grouped product items
Size Price Stock Qty
25mg
$1,655.00
In stock
50mg
$2,115.00
In stock
100mg
$2,720.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTGR5 Agonist 3 is a cholic acid derivative that selectively activates the TGR5 receptor, exhibiting an EC50 of 5 μM. This compound is utilized in research to explore the role of TGR5 in various metabolic processes, including glucose and lipid metabolism. Its specific action makes it a valuable tool for studying the therapeutic potential of TGR5 modulation in diseases such as obesity and diabetes.
Product Information
Catalog NumA60415
FormulaC28H48O5
Molecular Weight464.68
CAS Number2148317-51-3
SMILESC[C@@H]([C@]1(CC[C@]2([C@@]3([C@](O)(C[C@@]4(C[C@@H](CC[C@@]4([C@]3(C[C@@H]([C@]12C)O)[H])C)O)[H])CCCC)[H])[H])[H])CCC(O)=O
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GPCR/G Protein > GPCR19