TGR5 Receptor Agonist 3 (Compound 19) is a selective agonist for the G-protein-coupled bile acid receptor 1 (TGR5), demonstrating enhanced safety by minimizing gallbladder-filling effects. It exhibits effective activation of human TGR5 with an EC50 of 16.4 nM and mouse TGR5 with an EC50 of 209 nM. This compound is valuable in research applications focusing on metabolic regulation, energy expenditure, and bile acid signaling pathways.
TGR5 Receptor Agonist 3 (Compound 19) is a selective agonist for the G-protein-coupled bile acid receptor 1 (TGR5), demonstrating enhanced safety by minimizing gallbladder-filling effects. It exhibits effective activation of human TGR5 with an EC50 of 16.4 nM and mouse TGR5 with an EC50 of 209 nM. This compound is valuable in research applications focusing on metabolic regulation, energy expenditure, and bile acid signaling pathways.
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