TH588

Catalog No.: A15537

MTH1 inhibitor

TH588

TH588 Chemical Structure

CAS NO. 1609960-31-7

TH588 is first-in-class nudix hydrolase family inhibitor that potently and selectively engage and inhibit the MTH1(IC50= 5 nM) in cells,

Availability: In stock

Package Price Qty
10 mg
$100.00
25 mg
$140.00
50 mg
$240.00
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Biological Activity

TH588 is first-in-class nudix hydrolase family inhibitor that potently and selectively engage and inhibit the MTH1(IC50= 5 nM) in cells,
Targets
MTH1 (NUDT1)
5 nM
In vitro DMSO Warmed: 19 mg/mL (64.36 mM)
Water Insoluble
Ethanol Warmed: 1 mg/mL (3.38 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.88 mL 169.39 mL 338.79 mL
0.5 mM 6.78 mL 33.88 mL 67.76 mL
1 mM 3.39 mL 16.94 mL 33.88 mL
5 mM 0.68 mL 3.39 mL 6.78 mL

*The above data is based on the productmolecular weight 295.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15537
Actions Inhibitor
CAS No. 1609960-31-7
Formula C13H12Cl2N4
M. Wt 295.17
Solubility DMSO
Purity >98%
Synonyms TH-588, TH 588
SMILES C1CC1NC2=NC(=NC(=C2)C3=C(C(=CC=C3)Cl)Cl)N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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