TH588

Catalog No.: A15537

MTH1 inhibitor

TH588

TH588 Chemical Structure

CAS NO. 1609960-31-7

TH588 is first-in-class nudix hydrolase family inhibitor that potently and selectively engage and inhibit the MTH1(IC50= 5 nM) in cells,

Availability: In stock

Package Price Qty
10 mg
$100.00
25 mg
$140.00
50 mg
$240.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

TH588 is first-in-class nudix hydrolase family inhibitor that potently and selectively engage and inhibit the MTH1(IC50= 5 nM) in cells,
Targets
MTH1 (NUDT1)
5 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.88 mL 169.39 mL 338.79 mL
0.5 mM 6.78 mL 33.88 mL 67.76 mL
1 mM 3.39 mL 16.94 mL 33.88 mL
5 mM 0.68 mL 3.39 mL 6.78 mL

*The above data is based on the productmolecular weight 295.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A15537
Actions Inhibitor
M. Wt 295.17
Formula C13H12Cl2N4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1609960-31-7
Synonyms TH-588, TH 588
SMILES C1CC1NC2=NC(=NC(=C2)C3=C(C(=CC=C3)Cl)Cl)N

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