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Thalidomide-NH-CBP/p300 ligand 2

Catalog No.: A40312
CBP/p300 PROTAC Degrader
Thalidomide-NH-CBP/p300 ligand 2 is a PROTAC-based degrader that targets the CBP and p300 proteins. This compound facilitates the selective degradation of these transcriptional coactivators, which are implicated in various cancers and other diseases. Its application in research includes the elucidation of the roles of CBP and p300 in transcriptional regulation and therapeutic development for conditions influenced by these proteins.
Thalidomide-NH-CBP/p300 ligand 2 2484739-21-9 CBP/p300 PROTAC Degrader
Grouped product items
Size Price Stock Qty
1mg
$215.00
In stock
5mg
$535.00
In stock
10mg
$925.00
In stock
25mg
$1,965.00
In stock
50mg
$3,200.00
In stock
100mg
$4,785.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionThalidomide-NH-CBP/p300 ligand 2 is a PROTAC-based degrader that targets the CBP and p300 proteins. This compound facilitates the selective degradation of these transcriptional coactivators, which are implicated in various cancers and other diseases. Its application in research includes the elucidation of the roles of CBP and p300 in transcriptional regulation and therapeutic development for conditions influenced by these proteins.
Product Information
Catalog NumA40312
FormulaC48H57F2N11O6
Molecular Weight922.03
CAS Number2484739-21-9
SMILESO=C(N1CC2=C(CC1)N(C3CCN(CC3)C(CCCCCCCNC4=CC=C5C(N(C6C(NC(CC6)=O)=O)C(C5=C4)=O)=O)=O)N=C2N7C8=C(CCC7)C=C(C9=CN(C)N=C9)C(C(F)F)=C8)NC
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

    V2

Epigenetics > Epigenetic Reader Domain
PROTAC > PROTAC Degrader