Fig. 1 · Structure
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Thiacetazone
Antitubercular agent
Thiacetazone, a thiourea-containing antitubercular agent, acts as an orally active antibiotic targeting Mycobacterium tuberculosis. This compound exhibits significant antibacterial activity with a minimum inhibitory concentration (MIC) of 0.1 μg/mL against the H37Rv strain. Thiacetazone is primarily utilized in research applications related to tuberculosis treatment and the development of new antitubercular therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 104-06-3 |
| Applications | Antitubercular agent |
| Formula | C10H12N4OS |
| Molecular Weight | 236.29 |
| Synonyms | Thioacetazone; Amithiozone |
| SMILES | CC(NC1=CC=C(/C=N/NC(N)=S)C=C1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.