Thrombospondin (TSP-1)-derived CD36 binding motif is a bioactive hexapeptide that targets CD36 and angiostatin. This peptide disrupts cell adhesion and migration by interfering with the interaction between cells and the extracellular matrix. Additionally, it demonstrates the capability to inhibit platelet aggregation and exhibits anti-tumor properties, particularly against colon cancer. Its applications encompass studies of cell adhesion dynamics, platelet function, and potential therapeutic strategies in oncology.
Thrombospondin (TSP-1)-derived CD36 binding motif is a bioactive hexapeptide that targets CD36 and angiostatin. This peptide disrupts cell adhesion and migration by interfering with the interaction between cells and the extracellular matrix. Additionally, it demonstrates the capability to inhibit platelet aggregation and exhibits anti-tumor properties, particularly against colon cancer. Its applications encompass studies of cell adhesion dynamics, platelet function, and potential therapeutic strategies in oncology.
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