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ThrRS-IN-3

ThrRS Inhibitor

ThrRS-IN-3 is a potent inhibitor of threonyl-tRNA synthetase (ThrRS) with an IC50 value of 19 nM and a Kd of 34 nM specifically for Salmonella enterica ThrRS. This compound exhibits significant antibacterial activity, making it a valuable reagent for research on bacterial protein synthesis and antimicrobial mechanisms. It may be utilized to investigate the role of ThrRS in bacterial growth and development.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3031483-23-2
Applications	ThrRS Inhibitor
Formula	C₃₁H₃₀Cl₂N₆O₅
Molecular Weight	637.51
SMILES	O=C(NC[C@@H](C1=CC(C2=CC(CN3)=C(C=C2)C3=O)=CC=C1)NC([C@@H](N)[C@@H](C)O)=O)CCN4C=NC5=C(C4=O)C=C(Cl)C(Cl)=C5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.