Tipifarnib S enantiomer

Catalog No.: A21787

FTase inhibitor

Tipifarnib S enantiomer

Tipifarnib S enantiomer Chemical Structure

CAS NO. 192185-71-0

Tipifarnib S enantiomer is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM. Tipifarnib S enantiomer is the less active isomer.

Availability: In stock

Package Price Qty
5 mg
$193.00
10 mg
$332.00
50 mg
$984.00
100 mg
$1,969.00
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Biological Activity

Tipifarnib S enantiomer is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM. Tipifarnib S enantiomer is the less active isomer.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.43 mL 102.17 mL 204.33 mL
0.5 mM 4.09 mL 20.43 mL 40.87 mL
1 mM 2.04 mL 10.22 mL 20.43 mL
5 mM 0.41 mL 2.04 mL 4.09 mL

*The above data is based on the productmolecular weight 489.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21787
Actions Inhibitor
M. Wt 489.4
Formula C27H22Cl2N4O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 192185-71-0
Synonyms (S)-(-)-R-115777, R115777, R 115777; IND-58359 S enantiomer, IND58359, IND 58359
SMILES O=C1N(C)C2=C(C=C([[email protected]](C3=CC=C(Cl)C=C3)(N)C4=CN=CN4C)C=C2)C(C5=CC=CC(Cl)=C5)=C1

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