Fig. 1 · Structure
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Tirofiban hydrochloride
Gp IIb/IIIa Receptor Antagonist
Tirofiban hydrochloride is a selective and reversible antagonist of the Gp IIb/IIIa receptor, effectively inhibiting fibrinogen binding and exhibiting potent antithrombotic properties. In addition to its primary function, Tirofiban hydrochloride promotes endothelial cell proliferation and migration through the upregulation of vascular endothelial growth factor (VEGF). This compound also plays a critical role in reducing myocardial no-reflow and ischemia-reperfusion injury by mitigating structural and endothelial dysfunction in ischemic myocardial tissues.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 142373-60-2 |
| Applications | Gp IIb/IIIa Receptor Antagonist |
| Formula | C22H37ClN2O5S |
| Molecular Weight | 477.06 |
| Synonyms | L700462 hydrochloride; MK383 hydrochloride |
| SMILES | CCCCS(N[C@H](C(O)=O)CC1=CC=C(C=C1)OCCCCC2CCNCC2)(=O)=O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.