TLX Agonist 3 is a potent and selective agonist of the tailless homolog (TLX, NR2E1) that exhibits an EC50 of 0.25 μM and a Kd of 1.6 μM. This compound demonstrates high specificity for TLX over related nuclear receptors and promotes TLX oligomerization with an EC50 of 5.0 μM. TLX Agonist 3 is utilized in research focused on neurodegenerative diseases, providing insights into the role of TLX in neuronal function and disease mechanisms.
TLX Agonist 3 is a potent and selective agonist of the tailless homolog (TLX, NR2E1) that exhibits an EC50 of 0.25 μM and a Kd of 1.6 μM. This compound demonstrates high specificity for TLX over related nuclear receptors and promotes TLX oligomerization with an EC50 of 5.0 μM. TLX Agonist 3 is utilized in research focused on neurodegenerative diseases, providing insights into the role of TLX in neuronal function and disease mechanisms.
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