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TNO211

MMP Fluorogenic Substrate

TNO211 is a fluorogenic substrate designed for the specific detection of matrix metalloproteinase (MMP) activity. It contains a cleavable Gly-Leu bond, allowing for the precise identification of MMPs, and features a fluorophore/quencher pair consisting of EDANS and Dabcyl. This reagent operates optimally at excitation/emission wavelengths of 340/485 nm, making it suitable for various applications in biochemical and molecular biology research focused on MMP functions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Substrate
CAS Number	193475-71-7
Applications	MMP Fluorogenic Substrate
Formula	C₆₃H₈₈N₁₆O₁₄S
Molecular Weight	1325.54
Synonyms	Dabcyl-GABA-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2
SMILES	S(=O)(=O)(O)C=1C2=C(C(NCCNC(CC[C@H](NC([C@@H](NC(CNC([C@@H](NC(=O)[C@H]3N(C(CCCNC(=O)C4=CC=C(N=NC5=CC=C(N(C)C)C=C5)C=C4)=O)CCC3)CCC(N)=O)=O)=O)CC(C)C)=O)C(N[C@H](C(N[C@@H](CCCCN)C(N)=O)=O)C)=O)=O)=CC=C2)C=CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.