Tolfenamic acid-13C6

Catalog No.: A64441
Stable Isotope
Tolfenamic acid-13C6 is a stable isotope-labeled derivative of Tolfenamic acid, a non-steroidal anti-inflammatory and anti-cancer agent. It selectively inhibits COX-2 with an IC50 of 13.49 μM in LPS-treated canine DH82 monocyte/macrophage cells, while exhibiting no inhibitory effect on COX-1. This reagent is valuable for studying COX-2-related pathways and assessing the pharmacokinetics and metabolism of Tolfenamic acid in various biological contexts.
Grouped product items
Size Price Stock Qty
1mg
$135.00
In stock
5mg
$335.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
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Nature Volume 622 Issue 7982 (2023)
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Nature volume 551, pages639-643 (2017)
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Biological Activity
DescriptionTolfenamic acid-13C6 is a stable isotope-labeled derivative of Tolfenamic acid, a non-steroidal anti-inflammatory and anti-cancer agent. It selectively inhibits COX-2 with an IC50 of 13.49 μM in LPS-treated canine DH82 monocyte/macrophage cells, while exhibiting no inhibitory effect on COX-1. This reagent is valuable for studying COX-2-related pathways and assessing the pharmacokinetics and metabolism of Tolfenamic acid in various biological contexts.
Product Information
Catalog NumA64441
FormulaC813C6H12ClNO2
Molecular Weight267.66
CAS Number1420043-61-3
SMILESOC([13C]([13CH]=[13CH][13CH]=[13CH]1)=[13C]1NC2=C(C(Cl)=CC=C2)C)=O
SynonymsGEA 6414-13C6
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