Tolfenamic acid-d4 is a deuterated form of Tolfenamic Acid, a selective non-steroidal anti-inflammatory drug that primarily targets cyclooxygenase-2 (COX-2). It exhibits significant anti-inflammatory and potential anti-cancer properties, with an IC50 of 13.49 μM in LPS-treated canine DH82 monocyte/macrophage cells, while having no impact on COX-1 activity. Tolfenamic acid-d4 can be utilized in various research applications, including studies focused on inflammation and cancer biology, as well as in pharmacokinetic and metabolic profiling.
Tolfenamic acid-d4 is a deuterated form of Tolfenamic Acid, a selective non-steroidal anti-inflammatory drug that primarily targets cyclooxygenase-2 (COX-2). It exhibits significant anti-inflammatory and potential anti-cancer properties, with an IC50 of 13.49 μM in LPS-treated canine DH82 monocyte/macrophage cells, while having no impact on COX-1 activity. Tolfenamic acid-d4 can be utilized in various research applications, including studies focused on inflammation and cancer biology, as well as in pharmacokinetic and metabolic profiling.
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