Topiroxostat-d4 is a deuterium-labeled derivative of Topiroxostat, a potent inhibitor of xanthine oxidoreductase (XOR) with an IC50 of 5.3 nM and a Ki of 5.7 nM. This compound exhibits weak inhibitory activity on CYP3A4 (18.6%), making it suitable for in-depth metabolic studies. Topiroxostat is primarily utilized for research related to hyperuricemia, targeting pathways involved in uric acid production and metabolism.
Topiroxostat-d4 is a deuterium-labeled derivative of Topiroxostat, a potent inhibitor of xanthine oxidoreductase (XOR) with an IC50 of 5.3 nM and a Ki of 5.7 nM. This compound exhibits weak inhibitory activity on CYP3A4 (18.6%), making it suitable for in-depth metabolic studies. Topiroxostat is primarily utilized for research related to hyperuricemia, targeting pathways involved in uric acid production and metabolism.
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