TP-434 (Eravacycline)

TP-434 is a novel, broad-spectrum fluorocycline antibiotic with activity against bacteria expressing major antibiotic resistance mechanisms including tetracycline-specific efflux and ribosomal-protection.
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TP-434 5mg
TP-434 10mg
TP-434 25mg
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Adooq Products cited in reputable paper
Adooq's TP-434 (Eravacycline) has been cited by 4 publications
  • Hitender Gautam, .et al. , Indian J Med Microbiol, 2024, Mar-Apr:48:100565 PMID: 38522746
  • Zewen Wen, .et al. , J Antibiot (Tokyo), 2022, Sep;75(9):498-508 PMID: 35896611
  • Fan Zhang, .et al. , BMC Microbiol, 2018, 18: 211 PMID: 30545293
  • Jin-xin Zheng, .et al. , Emerg Microbes Infect, 2018, 7: 139 PMID: 30068997
  • Biological Activity
    Discription TP-434 is a novel, broad-spectrum fluorocycline antibiotic with activity against bacteria expressing major antibiotic resistance mechanisms including tetracycline-specific efflux and ribosomal-protection.
    Targets
    Target Value
    Product Information
    Catalog Num A13887
    Formula C27H31FN4O8
    Molecular Weight 558.555
    CAS Number 1207283-85-9
    SMILES CN(C)[C@H]1[C@@H]2C[C@@H]3CC4=C(C=C(C(=C4C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O)NC(=O)CN5CCCC5)F
    Synonyms Eravacycline, TP434, TP 434
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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    This equation is commonly abbreviated as: C1V1 = C2V2

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