TP-α is a glucagon-selective two-photon fluorescent probe with a dissociation constant (Kd) of 65 μM. This probe directly interacts with glucagon, resulting in a significant enhancement of fluorescence. TP-α selectively stains viable glucagon-secreting α cells within pancreatic islets, facilitating the visualization of their localization, distribution, and availability. It is particularly valuable for applications in diabetes research.
TP-α is a glucagon-selective two-photon fluorescent probe with a dissociation constant (Kd) of 65 μM. This probe directly interacts with glucagon, resulting in a significant enhancement of fluorescence. TP-α selectively stains viable glucagon-secreting α cells within pancreatic islets, facilitating the visualization of their localization, distribution, and availability. It is particularly valuable for applications in diabetes research.
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