Tr-PEG5-OH is a non-cleavable polyethylene glycol (PEG) linker designed for use in the synthesis of antibody-drug conjugates (ADCs). Comprising five PEG units, this versatile linker facilitates the conjugation of antibodies to cytotoxic drugs, enhancing the therapeutic efficacy and selectivity of ADCs. Additionally, Tr-PEG5-OH serves as a PEG-based PROTAC linker, enabling the development of proteolysis-targeting chimeras for targeted protein degradation studies.
Tr-PEG5-OH is a non-cleavable polyethylene glycol (PEG) linker designed for use in the synthesis of antibody-drug conjugates (ADCs). Comprising five PEG units, this versatile linker facilitates the conjugation of antibodies to cytotoxic drugs, enhancing the therapeutic efficacy and selectivity of ADCs. Additionally, Tr-PEG5-OH serves as a PEG-based PROTAC linker, enabling the development of proteolysis-targeting chimeras for targeted protein degradation studies.
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