Trametinib (DMSO solvate)

Name: Trametinib (DMSO solvate)
Brand: Adooq Bioscience
SKU: A21450
Rating: 5 (1 reviews)

Catalog No.: A21450

MEK inhibitor

Adooq's Trametinib (DMSO solvate) has been cited by 1 publications

Trametinib DMSO solvate (GSK-1120212 (DMSO solvate);JTP-74057 (DMSO solvate)) is a potent MEK inhibitor that specifically inhibits MEK1/2, with an IC50 value of about 2 nM.

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Trametinib (DMSO solvate) 1187431-43-1 MEK inhibitor

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Grouped product items
Size	Price	Stock
5mg	$25.00	In stock
10mg	$35.00	In stock
25mg	$45.00	In stock
50mg	$50.00	In stock
100mg	$75.00	In stock
200mg	$110.00	In stock
*10mM 1mL in DMSO**	$45.00	In stock
Bulk Size	Bulk Discount

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Adooq Products cited in reputable paper

Adooq's Trametinib (DMSO solvate) has been cited by 1 publications

Yuki Shimizu, .et al. , Cancer Lett, 2022, Sep 1;543 PMID: 35724767

Biological Activity

Description

Trametinib DMSO solvate (GSK-1120212 (DMSO solvate);JTP-74057 (DMSO solvate)) is a potent MEK inhibitor that specifically inhibits MEK1/2, with an IC50 value of about 2 nM.

Targets

Target	Value

Product Information

Catalog Num	A21450
Formula	C28H29FIN5O5S
Molecular Weight	693.53
CAS Number	1187431-43-1
SMILES	CN1C(C(C)=C(N(C(N(C2=O)C3CC3)=O)C4=CC=CC(NC(C)=O)=C4)C2=C1NC5=CC=C(C=C5F)I)=O.CS(C)=O
Synonyms	GSK-1120212 (DMSO solvate), GSK1120212, GSK 1120212; JTP-74057 (DMSO solvate), JTP74057, JTP 74057
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂