Trametinib (DMSO solvate)

Trametinib DMSO solvate (GSK-1120212 (DMSO solvate);JTP-74057 (DMSO solvate)) is a potent MEK inhibitor that specifically inhibits MEK1/2, with an IC50 value of about 2 nM.
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Trametinib (DMSO solvate) 10mg
Special Price $43.20 Regular Price $54.00
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Trametinib (DMSO solvate) 25mg
Special Price $86.40 Regular Price $108.00
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Trametinib (DMSO solvate) 50mg
Special Price $148.80 Regular Price $186.00
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Trametinib (DMSO solvate) 100mg
Special Price $254.40 Regular Price $318.00
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Adooq Products cited in reputable paper
Adooq's Trametinib (DMSO solvate) has been cited by 1 publications
  • Yuki Shimizu, .et al. , Cancer Lett, 2022, Sep 1;543 PMID: 35724767
  • Biological Activity
    Discription Trametinib DMSO solvate (GSK-1120212 (DMSO solvate);JTP-74057 (DMSO solvate)) is a potent MEK inhibitor that specifically inhibits MEK1/2, with an IC50 value of about 2 nM.
    Targets
    Target Value
    Product Information
    Catalog Num A21450
    Formula C28H29FIN5O5S
    Molecular Weight 693.53
    CAS Number 1187431-43-1
    SMILES CN1C(C(C)=C(N(C(N(C2=O)C3CC3)=O)C4=CC=CC(NC(C)=O)=C4)C2=C1NC5=CC=C(C=C5F)I)=O.CS(C)=O
    Synonyms GSK-1120212 (DMSO solvate), GSK1120212, GSK 1120212; JTP-74057 (DMSO solvate), JTP74057, JTP 74057
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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