Triphenylphosphinechlorogold

Catalog No.: A86959
Apoptosis Inducer
Triphenylphosphinechlorogold (Chloro(triphenylphosphine)gold(I)) targets apoptosis induction and acts as a catalyst in various biochemical reactions. This gold complex demonstrates significant lipoxygenase (LOX) inhibitory activity, leading to cell cycle arrest and apoptosis in cancer cells. Additionally, it catalyzes the peroxidation of linoleic acid and shows antiproliferative effects against breast cancer cell lines, contributing to its application in cancer research. A weak interaction with DNA may be involved in its mechanism of action, further highlighting its potential in therapeutic exploration.
Grouped product items
Size Price Stock Qty
50mg
$20.00
In stock
100mg
$35.00
In stock
250mg
$70.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTriphenylphosphinechlorogold (Chloro(triphenylphosphine)gold(I)) targets apoptosis induction and acts as a catalyst in various biochemical reactions. This gold complex demonstrates significant lipoxygenase (LOX) inhibitory activity, leading to cell cycle arrest and apoptosis in cancer cells. Additionally, it catalyzes the peroxidation of linoleic acid and shows antiproliferative effects against breast cancer cell lines, contributing to its application in cancer research. A weak interaction with DNA may be involved in its mechanism of action, further highlighting its potential in therapeutic exploration.
Product Information
Catalog NumA86959
FormulaC18H15AuClP
Molecular Weight494.71
CAS Number14243-64-2
SMILESCl[Au][P](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3
SynonymsChloro(triphenylphosphine)gold(I)
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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