Biological Activity
Tyrphostin AG 183 inhibits EGFR (epidermal growth factor receptor) tyrosine kinase (IC50 = 800 nM).
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 37.29 mL | 186.43 mL | 372.86 mL |
0.5 mM | 7.46 mL | 37.29 mL | 74.57 mL |
1 mM | 3.73 mL | 18.64 mL | 37.29 mL |
5 mM | 0.75 mL | 3.73 mL | 7.46 mL |
*The above data is based on the productmolecular weight 268.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A13588 |
---|---|
Actions | Inhibitor |
CAS No. | 126433-07-6 |
Formula | C13H8N4O3 |
M. Wt | 268.2 |
Solubility | DMSO |
Purity | >98% |
Synonyms | Tyrphostin 51, AG183, AG-183 |
SMILES | C1=C(C=C(C(=C1O)O)O)/C=C(\C#N)/C(=C(C#N)C#N)N |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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