Tyrphostin AG 183

Catalog No.: A13588

EGFR inhibitor

Tyrphostin AG 183

Tyrphostin AG 183 Chemical Structure

CAS NO. 126433-07-6

Tyrphostin AG 183 inhibits EGFR (epidermal growth factor receptor) tyrosine kinase (IC50 = 800 nM).

Availability: In stock

Package Price Qty
10 mg
$50.00
25 mg
$100.00
50 mg
$170.00
100 mg
$300.00
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Biological Activity

Tyrphostin AG 183 inhibits EGFR (epidermal growth factor receptor) tyrosine kinase (IC50 = 800 nM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.29 mL 186.43 mL 372.86 mL
0.5 mM 7.46 mL 37.29 mL 74.57 mL
1 mM 3.73 mL 18.64 mL 37.29 mL
5 mM 0.75 mL 3.73 mL 7.46 mL

*The above data is based on the productmolecular weight 268.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13588
Actions Inhibitor
CAS No. 126433-07-6
Formula C13H8N4O3
M. Wt 268.2
Solubility DMSO
Purity >98%
Synonyms Tyrphostin 51, AG183, AG-183
SMILES C1=C(C=C(C(=C1O)O)O)/C=C(\C#N)/C(=C(C#N)C#N)N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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