Ursodeoxycholic acid-d4 is a deuterium-labeled version of ursodeoxycholic acid, serving as a stable isotope for various biochemical studies. This secondary bile acid, produced by the conversion of (cheno)deoxycholic acid by intestinal microbiota, plays a crucial role in maintaining intestinal barrier integrity and is vital for lipid metabolism. It functions as a signaling molecule by interacting with receptors such as the G-protein coupled bile acid receptor 5 (TGR5) and the farnesoid X receptor (FXR). Ursodeoxycholic acid-d4 is applicable in research focused on hepatic and gastrointestinal diseases, and it demonstrates potential in modulating ACE2 expression, thereby contributing to investigations on SARS-CoV-2 infection.
Ursodeoxycholic acid-d4 is a deuterium-labeled version of ursodeoxycholic acid, serving as a stable isotope for various biochemical studies. This secondary bile acid, produced by the conversion of (cheno)deoxycholic acid by intestinal microbiota, plays a crucial role in maintaining intestinal barrier integrity and is vital for lipid metabolism. It functions as a signaling molecule by interacting with receptors such as the G-protein coupled bile acid receptor 5 (TGR5) and the farnesoid X receptor (FXR). Ursodeoxycholic acid-d4 is applicable in research focused on hepatic and gastrointestinal diseases, and it demonstrates potential in modulating ACE2 expression, thereby contributing to investigations on SARS-CoV-2 infection.
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