Fig. 1 · Structure
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V-06-018
LasR Antagonist
V-06-018 is a potent antagonist of the LasR receptor, exhibiting an IC50 value of 5.2 µM. This compound serves as a valuable chemical probe for investigating quorum sensing mechanisms in Pseudomonas aeruginosa. Its ability to disrupt LasR-mediated signaling makes it a key tool for studying bacterial communication and developing strategies against biofilm-associated infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 299927-26-7 |
| Applications | LasR Antagonist |
| Formula | C18H27NO2 |
| Molecular Weight | 289.41 |
| SMILES | O=C(CC(C1=CC=CC=C1)=O)NCCCCCCCCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.