VcMMAE

Catalog No.: A14362

VcMMAE Chemical Structure

CAS NO. 646502-53-6

VcMMAE is an antibody-drug conjugate (ADC) with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc).

Availability: In stock

Package Price Qty
1 mg

Regular Price: $70.00

Special Price $56.00

2 mg

Regular Price: $120.00

Special Price $96.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

VcMMAE is an antibody-drug conjugate (ADC) with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 7.6 mL 37.98 mL 75.95 mL
0.5 mM 1.52 mL 7.6 mL 15.19 mL
1 mM 0.76 mL 3.8 mL 7.6 mL
5 mM 0.15 mL 0.76 mL 1.52 mL

*The above data is based on the productmolecular weight 1316.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14362
M. Wt 1316.63
Formula C68H105N11O15
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 646502-53-6
Synonyms Vedotin
SMILES CC[[email protected]](C)[[email protected]@H]([[email protected]@H](CC(=O)N1CCC[[email protected]]1[[email protected]@H]([[email protected]@H](C)C(=O)N[[email protected]](C)[[email protected]](C2=CC=CC=C2)O)OC)OC)N(C)C(=O)[[email protected]](C(C)C)NC(=O)[[email protected]](C(C)C)N(C)C(=O)OCC3=CC=C(C=C3)NC(=O)[[email protected]](CCCNC(=O)N)NC(=O)[[email protected]](C(C)C)NC(=O)CCCCCN4C(=O)C=CC4=O

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