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|Storage||at -20°C 3 years Powder|
|SMILES code||CC[[email protected]](C)[[email protected]@H]([[email protected]@H](CC(=O)N1CCC[[email protected]]1[[email protected]@H]([[email protected]@H](C)C(=O)N[[email protected]](C)[[email protected]](C2=CC=CC=C2)O)OC)OC)N(C)C(=O)[[email protected]](C(C)C)NC(=O)[[email protected]](C(C)C)N(C)C(=O)OCC3=CC=C(C=C3)NC(=O)[[email protected]](CCCNC(=O)N)NC(=O)[[email protected]](C(C)C)NC(=O)CCCCCN4C(=O)C=CC4=O|
|Chemical Name||Maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl-monomethyl auristatin E|
|VcMMAE is an antibody-drug conjugate (ADC) with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc).|
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||7.6 mL||37.98 mL||75.95mL|
|0.5 mM||1.52 mL||7.6 mL||15.19 mL|
|1 mM||0.76 mL||3.8 mL||7.6 mL|
|5 mM||0.15 mL||0.76 mL||1.52 mL|
*The above data is based on the productmolecular weight 1316.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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