Vincristine-d3-1 sulfate is a deuterium-labeled derivative of Vincristine sulfate, a potent antitumor vinca alkaloid. It acts by inhibiting microtubule polymerization, leading to cell cycle arrest at the metaphase stage, which is critical in cancer treatment. With a Ki of 85 nM for microtubule binding, this stable isotope is valuable for mechanistic studies and quantitative applications in cancer research.
Vincristine-d3-1 sulfate is a deuterium-labeled derivative of Vincristine sulfate, a potent antitumor vinca alkaloid. It acts by inhibiting microtubule polymerization, leading to cell cycle arrest at the metaphase stage, which is critical in cancer treatment. With a Ki of 85 nM for microtubule binding, this stable isotope is valuable for mechanistic studies and quantitative applications in cancer research.
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