Wedelolactone

Catalog No.: A14804

IKK Inhibitor II

Wedelolactone

Wedelolactone Chemical Structure

CAS NO. 524-12-9

Wedelolactone, a compound originally extracted from Eclipta alba, has been shown to inhibit caspase-11, which is a key regulator of proinflammatory cytokine IL-1β maturation and pathological apoptosis.

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Package Price Qty
10 mg
$140.00
25 mg
$280.00
50 mg
$500.00
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  • Shigetoshi Yokoyama, .et al. A novel pathway of LPS uptake through syndecan-1 leading to pyroptotic cell death, eLife, 2018, 7: e37854 PMID: 30526845

Biological Activity

Wedelolactone, a compound originally extracted from Eclipta alba, has been shown to inhibit caspase-11, which is a key regulator of proinflammatory cytokine IL-1β maturation and pathological apoptosis.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.82 mL 159.08 mL 318.17 mL
0.5 mM 6.36 mL 31.82 mL 63.63 mL
1 mM 3.18 mL 15.91 mL 31.82 mL
5 mM 0.64 mL 3.18 mL 6.36 mL

*The above data is based on the productmolecular weight 314.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14804
Actions Inhibitor
M. Wt 314.3
Formula C16H10O7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 524-12-9
Synonyms IKK Inhibitor II, Eclipta alba
SMILES COC1=CC(=C2C(=C1)OC(=O)C3=C2OC4=CC(=C(C=C43)O)O)O

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