Fig. 1 · Structure
Documents & Downloads
Wf-516 hydrochloride
Serotonin Transporter Inhibitor
Wf-516 hydrochloride is a selective inhibitor of the serotonin transporter (SERT) as well as an antagonist of 5-HT1A and 5-HT2A receptors, exhibiting Ki values of 5 nM and 40 nM for the respective receptors in human systems. This compound demonstrates significant antidepressant activity, making it a valuable tool in the study of serotonin-related disorders and the development of novel antidepressant therapies. Its unique pharmacological profile positions Wf-516 hydrochloride as an important reagent for research in neuropharmacology and mood disorder pathology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 310392-93-9 |
| Applications | Serotonin Transporter Inhibitor |
| Formula | C25H26Cl3N3O4 |
| Molecular Weight | 538.85 |
| SMILES | O[C@H](COC1=C2C=C(C3=NN=C(C)O3)OC2=CC=C1)CN(CC4)CCC4C5=CC=C(Cl)C(Cl)=C5.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.