Xelafaslatide

Catalog No.: A64891
Fas receptor Antagonist
Xelafaslatide is a Fas receptor antagonist that effectively inhibits Fas receptor signaling, thereby blocking downstream apoptosis and inflammatory pathways. This compound demonstrates significant potential in suppressing neuroinflammation and microglial activation in glaucoma models, offering protection to retinal ganglion cells and preventing axonal degeneration. Xelafaslatide is relevant for research focused on glaucoma and related neurodegenerative conditions.
Grouped product items
Size Price Stock Qty
1mg
$40.00
In stock
5mg
$90.00
In stock
10mg
$150.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionXelafaslatide is a Fas receptor antagonist that effectively inhibits Fas receptor signaling, thereby blocking downstream apoptosis and inflammatory pathways. This compound demonstrates significant potential in suppressing neuroinflammation and microglial activation in glaucoma models, offering protection to retinal ganglion cells and preventing axonal degeneration. Xelafaslatide is relevant for research focused on glaucoma and related neurodegenerative conditions.
Product Information
Catalog NumA64891
FormulaC71H100N18O16
Molecular Weight1461.66
CAS Number2040964-58-5
SequenceHis-His-Ile-Tyr-Leu-Gly-Ala-Val-Asn-Tyr-Ile-Tyr-NH2
Sequence shorteningHHIYLGAVNYIY-NH2
SMILES[C@H](CC1=CC=C(O)C=C1)(C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(N)=O)=O)[C@H](CC)C)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)NC([C@@H](NC([C@H](CC4=CN=CN4)NC([C@H](CC5=CN=CN5)N)=O)=O)[C@H](CC)C)=O)=O)CC(C)C)=O)=O)C)=O)[C@@H](C)C)=O)CC(N)=O)=O
SynonymsONL-1204
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