You have no items in your shopping cart.
Publications citing Adooq Products
Chemical Information
| Catalog Num | A13069 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 515.65 |
| Formula | C28H37N9O |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 898280-07-4 |
| Synonyms | No |
| SMILES | CC(C)C1=NOC(=C1)CNC2=NC(=CC(=N2)NC3=NNC(=C3)C4CC4)N5CCN(CC5)C |
Description |
XL228 is a protein kinase inhibitor targeting IGF1R, the AURORA kinases, FGFR1-3, ABL and SRC family kinases. XL228 is an Aurora A inhibitor (IC50, f3 nmol/L) that has shown potent biochemical activity against ABL1 (Ki, 5 nmol/L), as well as the BCR-ABL1 T315I (Ki, 1.4 nmol/L) kinases. | |||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.39 mL | 96.96 mL | 193.93mL |
| 0.5 mM | 3.88 mL | 19.39 mL | 38.79 mL |
| 1 mM | 1.94 mL | 9.7 mL | 19.39 mL |
| 5 mM | 0.39 mL | 1.94 mL | 3.88 mL |
*The above data is based on the productmolecular weight 515.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Ordering online
To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.
To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.
When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards. We will then liaise with you or your purchasing department to confirm the order.
Found your products but not ready to order?
Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.
Ordering offline
You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order. Our contact details are:
- Tel: 866-930-6790
- Fax: 323-606-8156
- Email: [email protected]
We require the following information to process your order:
- The catalog number for each product.
- Your email address or fax number.
- Your name and telephone number.
- Shipping address and billing address.
- Purchase order numbers.
Similar product(s)
Special Price Starting at:
$72.00
NVP-AEW541 is a selective IGF-1R kinase inhibitor that inhibits the autophosphorylation activity of IGF-1R (IC50 = 0.086 uM) and prevents IGF-1-mediated survival and proliferation of MCF-7 cells (IC50 ...
Special Price Starting at: $72.00
Special Price Starting at:
$90.00
PQ 401 is a cell-permeable phenylquinolinyl-urea compound that inhibits IGF-1R autophosphorylation. ...
Special Price Starting at: $90.00
Special Price Starting at:
$54.00
AG-1024 (Tyrphostin) is a specific inhibitor of insulin-like growth factor-1 (IGF-1) and insulin receptor tyrosine kinase activity. Exhibits lower IC50 values for IGF-1 than for the insulin receptor. ...
Special Price Starting at: $54.00
Special Price Starting at:
$54.00
BMS-754807 is an efficacious, orally active growth factor 1 receptor/insulin receptor family-targeted kinase inhibitor that may act in combination with a wide array of established anticancer agents. ...
Special Price Starting at: $54.00
Special Price Starting at:
$45.00
OSI-906 is a potential first-in-class selective small molecule, dual kinase inhibitor of both insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (IR). ...
Special Price Starting at: $45.00
Special Price Starting at:
$30.00
Picropodophyllin (AXL1717) is the first targeted oral small-molecule IGF-1 receptor inhibitor with no effect on the insulin receptor. ...
Special Price Starting at: $30.00
Special Price Starting at:
$99.00
NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM. ...
Special Price Starting at: $99.00
Special Price Starting at:
$72.00
GSK1904529A selectively inhibits IGF-IR and IR with IC(50)s of 27 and 25 nmol/L, respectively. ...
Special Price Starting at: $72.00
Special Price Starting at:
$120.00
BMS-536924 is an effective inhibitor of IGF-IR, causing a reversion of an IGF-IR - mediated transformed phenotype. ...
Special Price Starting at: $120.00
Keywords:buy XL-228 | XL-228 Supplier | purchase XL-228 | XL-228 cost | XL-228 manufacturer | order XL-228 | XL-228 distributor | buy 898280-07-4| 898280-07-4 Supplier | purchase 898280-07-4 | 898280-07-4 cost | 898280-07-4 manufacturer | order 898280-07-4 | 898280-07-4 distributor
We Using Safe Payments:
