Z-LRGG-AMC

Catalog No.: A92813
Fluorescent Substrate
Z-LRGG-AMC (Z-Leu-Arg-Gly-Gly-AMC) is a fluorescent substrate that specifically targets proteases for hydrolysis, resulting in the release of the fluorescent molecule 7-amino-4-methylcoumarin (AMC). This compound is utilized in various research applications, particularly for studying protease activity in different biological systems. The fluorescence of AMC can be detected at an excitation/emission wavelength of 360/460 nm, making Z-LRGG-AMC a valuable tool for quantitative protease assays.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionZ-LRGG-AMC (Z-Leu-Arg-Gly-Gly-AMC) is a fluorescent substrate that specifically targets proteases for hydrolysis, resulting in the release of the fluorescent molecule 7-amino-4-methylcoumarin (AMC). This compound is utilized in various research applications, particularly for studying protease activity in different biological systems. The fluorescence of AMC can be detected at an excitation/emission wavelength of 360/460 nm, making Z-LRGG-AMC a valuable tool for quantitative protease assays.
Product Information
Catalog NumA92813
FormulaC34H44N8O8
Molecular Weight692.76
CAS Number167698-68-2
Sequence{Z}-Leu-Arg-Gly-Gly-{AMC}
Sequence shortening{Z}-LRGG-{AMC}
SynonymsZ-Leu-Arg-Gly-Gly-AMC
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2