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ZINC61142882

Catalog No.: A53408
SARS-CoV-2 Inhibitor
ZINC61142882 is an inhibitor of the SARS-CoV-2 Nsp14 N7-Methyltransferase, exhibiting an IC50 value of 6 μM. This compound demonstrates antiviral activity by disrupting viral RNA cap methylation, which is essential for RNA stability and immune evasion. It is suitable for research focused on COVID-19 therapeutic development and the exploration of viral RNA modifications.
ZINC61142882 3034181-87-5 SARS-CoV-2 Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionZINC61142882 is an inhibitor of the SARS-CoV-2 Nsp14 N7-Methyltransferase, exhibiting an IC50 value of 6 μM. This compound demonstrates antiviral activity by disrupting viral RNA cap methylation, which is essential for RNA stability and immune evasion. It is suitable for research focused on COVID-19 therapeutic development and the exploration of viral RNA modifications.
Product Information
Catalog NumA53408
FormulaC16H11BrN4O3
Molecular Weight387.19
CAS Number3034181-87-5
SMILESO=C(C1=NNC(C2=CC=CO2)=C1)OCC3=CN4C(C=CC(Br)=C4)=N3
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Microbiology > SARS-CoV