ZM223

Catalog No.: A17174

NEDD8 activating enzyme (NAE) inhibitor

ZM223

ZM223 Chemical Structure

CAS NO. 2031177-48-5

ZM223 is a non-sulfamide NEDD8 activating enzyme (NAE) inhibitor that inhibits HCT116 colon cancer cells with an IC50 value of 100 nM.

Availability: In stock

Package Price Qty
5 mg
$380.00
10 mg
$680.00
50 mg
$1,980.00
100 mg
$3,120.00
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Biological Activity

ZM223 is a non-sulfamide NEDD8 activating enzyme (NAE) inhibitor that inhibits HCT116 colon cancer cells with an IC50 value of 100 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.9 mL 99.5 mL 198.99 mL
0.5 mM 3.98 mL 19.9 mL 39.8 mL
1 mM 1.99 mL 9.95 mL 19.9 mL
5 mM 0.4 mL 1.99 mL 3.98 mL

*The above data is based on the productmolecular weight 502.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17174
Actions Inhibitor
M. Wt 502.53
Formula C23H17F3N4O2S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2031177-48-5
Synonyms ZM223
SMILES O=C(C1=CC=C(C(F)(F)F)C=C1)NC2=NC3=CC=C(NC(CSC4=CC=C(N)C=C4)=O)C=C3S2

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