AS-604850

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PI3K Inhibitor

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Catalog No. A11197

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AS-604850 5mg A11197-5

Regular Price: $60.00

Special Price: $48.00

AS-604850 10mg A11197-10

Regular Price: $100.00

Special Price: $80.00

AS-604850 50mg A11197-50

Regular Price: $420.00

Special Price: $336.00

AS-604850 100mg A11197-100

Regular Price: $620.00

Special Price: $496.00

AS-604850 10mM * 1mL in DMSO A11197-10mM-D

Regular Price: $93.00

Special Price: $74.40

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AS-604850 inhibited MCP-1-mediated monocyte chemotaxis with an IC50 value of 21 µM and reduced RANTES-induced peritoneal neutrophil recruitment in a murine model of leukocyte chemotaxis with an ED50 value of 42.4 mg/kg.

AS-604850

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Chemical Information

Catalog Num A11197
Actions Inhibitor
M. Wt 285.22
Formula C11H5F2NO4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 648449-76-7
Synonyms AS604850
SMILES code CCC1=COC2=CC(=O)C=C(C2=C1O)O
Chemical Name 5-​[(2,​2-​difluoro-​1,​3-​benzodioxol-​5-​yl)methylene]-​2,​4-​thiazolidinedione

Biological Activity

Description

AS-604850 inhibited MCP-1-mediated monocyte chemotaxis with an IC50 value of 21 µM and reduced RANTES-induced peritoneal neutrophil recruitment in a murine model of leukocyte chemotaxis with an ED50 value of 42.4 mg/kg.

Solubility

Solubility (25°C) * In vitro DMSO 57 mg/mL (199.84 mM)
Water <1 mg/mL (<1 mM)
Ethanol 5 mg/mL (17.53 mM)
In vivo 0.5% CMC/0.25% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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