CCT137690

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Aurora Kinase inhibitor

158 Customer Reviews
Catalog No. A11081

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
CCT137690 5mg A11081-5

Regular Price: $85.00

Special Price: $68.00

CCT137690 10mg A11081-10

Regular Price: $150.00

Special Price: $120.00

CCT137690 50mg A11081-50

Regular Price: $550.00

Special Price: $440.00

CCT137690 100mg A11081-100

Regular Price: $900.00

Special Price: $720.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

CCT137690 is a potent inhibitor of Aurora kinases that inhibits Aurora A and B kinases with low nanomolar IC50 values in both biochemical and cellular assays.

CCT137690

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Chemical Information

Catalog Num A11081
Actions Inhibitor
M. Wt 551.5
Formula C26H31BrN8O
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1095382-05-0
Synonyms CCT-137690
SMILES code CC1=CC(=NO1)CN2CCN(CC2)C3=C4C(=NC=C3Br)N=C(N4)C5=CC=C(C=C5)N6CCN(CC6)C
Chemical Name 6-Bromo-7-[4-[(5-methyl-3-isoxazolyl)methyl]-1-piperazinyl]-2-[4-(4-methyl-1-piperazinyl)phenyl]-3H-imidazo[4,5-b]pyridine

Biological Activity

Description
CCT137690 is a potent inhibitor of Aurora kinases that inhibits Aurora A and B kinases with low nanomolar IC50 values in both biochemical and cellular assays.
Targets
Aurora A Aurora C Aurora B
15 nM19 nM25 nM

Solubility

Solubility (25°C) * In vitro DMSO 4 mg/mL (7.25 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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