LDN193189 HCl

LDN193189 HCl is the hydrochloride salt of LDN193189. LDN193189 is a highly potent small molecule BMP inhibitor that inhibits BMP type I receptors ALK2 (IC50: 5 nM), ALK3 (IC50: 30 nM) and ALK6 (TGFβ1/BMP signaling) and subsequent SMAD phosphorylation.
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Product Name Price Stock Qty
LDN193189 HCl 5mg
$70.00
In stock
LDN193189 HCl 10mg
$90.00
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LDN193189 HCl 25mg
$160.00
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Adooq Products cited in reputable paper
Adooq's LDN193189 HCl has been cited by 1 publications
  • Brandon J.Peiffer, .et al. , Cell Chem Biol, 2019, 26, 1-10 PMID: 30827938
  • Biological Activity
    Discription LDN193189 HCl is the hydrochloride salt of LDN193189. LDN193189 is a highly potent small molecule BMP inhibitor that inhibits BMP type I receptors ALK2 (IC50: 5 nM), ALK3 (IC50: 30 nM) and ALK6 (TGFβ1/BMP signaling) and subsequent SMAD phosphorylation.
    Targets
    Target Value
    Product Information
    Catalog Num A11478
    Formula C25H22N6.HCl
    Molecular Weight 442.94
    CAS Number 1062368-62-0
    SMILES C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC6=CC=CC=C56)N=C3.Cl
    Synonyms LDN 193189
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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