YO-01027

Catalog No.: A11174
γ-secretase inhibitor
YO-01027 is a dipeptidic γ-secretase inhibitor, an antiAlzheimer agent.
Grouped product items
Product Name Price Stock Qty
YO-01027 5mg
$80.00
In stock
YO-01027 10mg
$140.00
In stock
YO-01027 25mg
$320.00
In stock
YO-01027 50mg
$520.00
In stock
YO-01027 10mM * 1mL in DMSO
$80.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's YO-01027 has been cited by 1 publications
  • Weijun Zhang, .et al. , Stem Cell Rev Rep, 2023, Jan 7 PMID: 36609902
  • Biological Activity
    Discription YO-01027 is a dipeptidic γ-secretase inhibitor, an antiAlzheimer agent.
    Targets
    Target Value
    Product Information
    Catalog Num A11174
    Formula C26H23F2N3O3
    Molecular Weight 463.48
    CAS Number 209984-56-5
    SMILES C[C@@H](C(=O)N[C@H]1C2=CC=CC=C2C3=CC=CC=C3N(C1=O)C)NC(=O)CC4=CC(=CC(=C4)F)F
    Synonyms YO01027, Dibenzazepine, Deshydroxy LY 411575
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 87 mg/mL (187.7 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 0.5% hydroxyethyl cellulose 5 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.58 mL 107.88 mL 215.76 mL
    0.5 mM 4.32 mL 21.58 mL 43.15 mL
    1 mM 2.16 mL 10.79 mL 21.58 mL
    5 mM 0.43 mL 2.16 mL 4.32 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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