2′-Hydroxy-5′-methoxyacetophenone

Catalog No.: A26139
Anti-inflammatory/Anti-tumor/Anti-mite Agent
2′-Hydroxy-5′-methoxyacetophenone is an acetophenone derivative that modulates inflammatory responses primarily through inhibition of the NF-κB signaling pathway. This compound demonstrates significant anti-tumor properties, particularly against ovarian cancer, and exhibits acaricidal activity. Additionally, it effectively inhibits enzymes such as α-amylase, collagenase, and aldose reductase with IC50 values of 0.928 μM, 3.264 μM, and 20.046 μM, respectively, indicating its potential in diabetes research.
Grouped product items
Size Price Stock Qty
1g
$20.00
In stock
10g
$25.00
In stock
25g
$35.00
In stock
100g
$80.00
In stock
500g
$400.00
In stock
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Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description2′-Hydroxy-5′-methoxyacetophenone is an acetophenone derivative that modulates inflammatory responses primarily through inhibition of the NF-κB signaling pathway. This compound demonstrates significant anti-tumor properties, particularly against ovarian cancer, and exhibits acaricidal activity. Additionally, it effectively inhibits enzymes such as α-amylase, collagenase, and aldose reductase with IC50 values of 0.928 μM, 3.264 μM, and 20.046 μM, respectively, indicating its potential in diabetes research.
Product Information
Catalog NumA26139
FormulaC9H10O3
Molecular Weight166.18
CAS Number705-15-7
SMILESCC(C1=CC(OC)=CC=C1O)=O
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